Senior/Lead Associate Metabolic Pharmacology (contract)

Company Overview

At Synlogic: We are Putting LIFE Into Medicines
We are pioneers in the development of Synthetic BioticTM medicines, a novel class of LIVING medicines intended to transform the lives of patients with a broad range of diseases ranging from genetic and acquired metabolic diseases to inflammation and cancer.

Every day our teams work tirelessly to drive to deliver on 4 aspirations:

  • People: LIVING each day with passion for building up and building out our Synlogic team
  • Platform: Expanding and enhancing the technology to generate and protect novel LIVING medicines with new and versatile mechanisms of action
  • Products: Rapidly developing and commercializing Synthetic Biotics that transform the LIVES of patients and their families
  • Promise: Building our company to launch multiple novel LIVING medicines – mastering a new frontier in medicine

We combine Human Logic and Science Logic to drive meaningful work, careers, and LIFE at Synlogic. We foster a people-focused environment grounded in: Compassion, Transparency, Collaboration & Fun, while adopting a patient-focused mindset to inspire: Innovation, Integrity, High Performance, and LIFE Changing Results.

We continue to build and enhance our organization. If you want a settled environment, pursuing a well-walked path then this environment is probably not for you. If you want to join a growing company, work hard, and challenge yourself to find solutions at a new frontier of medicines then we would love to hear from you.

Job Description

Senior/Lead Associate Metabolic Pharmacology – contract position

Synlogic is seeking a highly motivated biologist/pharmacologist to join the metabolic pharmacology team. An important emphasis of this position will be to establish and leverage mammalian in vivo model systems to address key questions about the efficacy of our engineered probiotics operating within the gastrointestinal system and the microbiome as an integral point for modulation of systemic metabolic disease. The successful candidate will work with our internal team, external experts and CROs to implement novel experimental systems to trace and characterize key metabolites and nutrients in the body. This is a unique and exciting opportunity to help develop synthetic biotics as therapies for inborn errors of metabolism, including UCD and PKU and other chronic metabolic diseases, and establish a new therapeutic modality that is leveraging the GI tract, and the power of synthetic biology towards the treatment of rare and intractable human diseases.


  • PhD with 2-5 years of relevant research experience in industry
  • Significant experience in research and development for rare or common metabolic disease indications and gastrointestinal physiology
  • Expertise in working with complex animal models in therapeutic areas such as inborn errors of metabolism, rare disease, metabolic diseases or liver diseases
  • Experience developing in vivo models and their application to therapeutic discovery and development
  • Strong analytical and problem solving capabilities
  • Strong publication track record
  • Strong oral and written communication skills
  • Experience working in cross functional multidisciplinary teams


To apply for this position please send your resume to:

Synlogic, Inc. is committed to equal employment opportunity. All applicants must have authorization to work in the U.S.